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Indications

  • Sagging Skin

  • Very dry skin

  • Frown lines

  • Fine wrinkles and deep folds


Results
Skin firmness + tensor effect + tone and hydration immediate effect.
Smoothening and suppleness of the skin.
Infuses the dermis with potent vitamins and anti-oxidants to rejuvenate and revitalize the skin.

Excessive skin wrinkles can be caused by: overall dehydration, excessive sun exposure, genetics, facial expressions, muscle atrophy, fatty acid deficiencies, hormone imbalances, nutrient deficiencies, and many other causes.A).






CHRONO-AGING
PATHOPHYSIOLOGY
Flattening of the dermal and skin interface with reduction of the dermal papilla. The epidermis becomes thinner and flattened, and cells of the basal and prickle layers appear heterogeneous and less well organized. Moreover, the collagen fibers become harder and the skin becomes less elastic. Elastic fibers start to disintegrate.
CAUSE
Formation of reactive oxygen species and induction of matrix metalloproteinases. ROS damage cellular components. This damage leads to increasing ROS and decreasing antioxidative capacities and finally to cellular ageing.Intrinsic skin ageing is also strongly influenced by hormonal changes. Production of sex hormones in the gonads, the pituitary and adrenal glands already gradually declines in the mid-twenties. Oestrogens and progesterone decay in line with the menopause. The deficiency in oestrogens and androgens causes dryness, wrinkling, epidermal atrophy, collagen breakdown and loss of elasticity.

PHOTO-AGING
PATHOPHYSIOLOGY
Laxity , wrinkles and a leather-like appearance caused directly by exposure to the sun or UV lamps. UV rays rapidly degrade the collagen and elastic fibers of the dermis that have no chance to restore anymore. Further relevant exogenous factors are exposure to tobacco smoke, airborne particulate matter, infrared radiation, ozone and malnutrition.
CAUSE
UV irradiation of skin increases hydrogen peroxides and other reactive oxygen species (ROS), and decreases anti-oxidant enzymes. increased ROS production alters gene and protein structure and function, leading to skin damage.
UVB is mainly absorbed in the epidermis, generating DNA-damage. UVA-light generate ROS, which damage lipids, proteins and DNA. UVA-light is exceptionally relevant in photoageing because of its high penetration depth.

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